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KMID : 0352420000190020249
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Keimyung Medical Journal
2000 Volume.19 No. 2 p.249 ~ p.258
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A Comparison of Carcinoembryonic Antigen Value Between Draining Blood and Peripheral Blood in Patients with Colorectal Cancer
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Abstract
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The aim of this study is to evaluate the relationship between histopathologic variables and carcinoembryonic antigen(CEA) level in peripheral and draining blood in the colorectal carcinoma.
We checked CEA levels in peripheral and draining venous blood from 20 patients with colorectal cancer and also examined tissue CEA in all of these patients. And we compared these with other variables including tumor location, depth of invasion, Dukes´ classification, tumor differentiation, nodal metastasis and lymphatic invasion.
The mean CEA value (7.85 ng/ml) of draining blood was higher than that(1.89 ng/ml) of the peripheral blood. Elevation of the CEA value in draining and peripheral blood was correlated with tumor differentiation, although the value was related to three other histologic variables including Dukes´ stage, node metastasis and lymphatic invasion as well. There was no correlation between plasma CEA level and tissue CEA expression.
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KEYWORD
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